Antimatter is primarily created in large particle accelerators like CERN, as well as through certain radioactive decay processes that emit positrons. PET scans utilize these positrons for medical diagnostics, although they do not create them but rather detect the gamma rays produced from positron-electron interactions. Recent findings suggest that lightning strikes can also produce antimatter. Research is ongoing to discover more efficient and effective methods of antimatter production, but current techniques remain limited. Further exploration of this topic can be found in the book "Mirror Matter," which discusses various aspects of antimatter manufacturing and usage.