To determine x(t) for a particle given initial conditions and a(x), one can start by recognizing that a(x) leads to a second-order autonomous differential equation, x''(t) = f(x(t)). The solution involves integrating the acceleration to find velocity, v(t), using the relationship v = dv/dx * dx/dt, which simplifies to a(x). After integrating to find v(x), the next step is to relate it back to x(t) through the equation dx/dt = v(x), leading to an integral that can be inverted to find x(t). This method may be complex and could require numerical integration for difficult functions.