Hydrolysis of Peptide Bonds on Chemsketch

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The discussion focuses on the hydrolysis of peptide bonds illustrated in a Chemsketch drawing. The user seeks clarification on which of the three peptide bonds would undergo hydrolysis, suggesting that any of the bonds could be reactive. They propose that the reaction might preferentially occur at the first bond due to the electronegativity of nitrogen compared to oxygen. The conversation highlights the importance of understanding peptide bond reactivity in biochemical processes. Overall, the inquiry emphasizes the complexity of peptide bond hydrolysis and its implications in chemistry.
melissajohn
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I drew this on chemsketch - http://img413.imageshack.us/my.php?image=peptide1kn3.jpg

I am trying to figure out what the results would be... there are 3 peptide bonds here... where would the reaction take place? the first, second or third peptide?

My guess would be that I could do the reaction on any... is that right?
 
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I'd say the HN=C b/c N is less electronegative than O.
 
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