Immuno Compromisation: Negative Effects & Living in a Bubble

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Immuno-compromised individuals face significant risks, as even harmless bacteria can become life-threatening. Temporary immuno-compromise may allow for protective measures, such as living in a sterile environment, but this is not foolproof. Patients undergoing treatments for conditions like leukemia or myeloma often need to remain in sterile rooms to minimize exposure to infections. The discussion also touches on the role of NFKappaB, questioning whether it is a gene or a protein, although this point is less central to the main concerns about immunity and safety.
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What are the negative effects that could happen to an immuno-compromised person? Could a temporarily immuno-compromised person live in a bubble/sterile room whatever and probably definately be fine?
 
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Is NFKappaB/what made the mice younger a gene or a protein?
 
bioquest said:
What are the negative effects that could happen to an immuno-compromised person? Could a temporarily immuno-compromised person live in a bubble/sterile room whatever and probably definately be fine?

Without immunity, any bacterium that's harmless to a healthy person could potentially kill the immuno-compromised individual.

If temporarily compromised, staying in a bubble could provide protection, but is not guaranteed. I believe most people who had leukemia or myeloma and had undergone treatments that compromised their immunities are required to stay in a sterile room until further notice.
 
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) The structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...

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