Importing a schematic from Proteus (.dsn file) to OrCAD is not straightforward, and users suggest utilizing Capture CIS for better compatibility. One participant mentions their experience with OrCAD layout, emphasizing the need to create a schematic first and generate an MNL file for the layout process. They also highlight the importance of component specifications before finalizing the PCB design. Users are encouraged to seek guidance from knowledgeable sources, such as university instructors, for further assistance. Overall, the discussion underscores the challenges and steps involved in transitioning from Proteus to OrCAD for PCB layout.