Importance of Y-chromosome in avoiding bladder cancer?

[Astronuc]

Males lose sex chromosome as they age. It could make cancer more deadly, study says​

https://www.yahoo.com/news/males-lose-sex-chromosome-age-211624452.html

Dan Theodorescu, director of Cedars-Sinai Cancer and corresponding author of the study, and a team of leading researchers from across the country published their findings in Nature on June 21.

As males age, they begin to lose some of their Y chromosomes due to rapid cell turnover, the study said.

“This study for the first time makes a connection that has never been made before between loss of the Y chromosome and the immune system’s response to cancer,” Theodorescu said in a June 21 release. “We discovered that loss of the Y chromosome allows bladder cancer cells to elude the immune system and grow very aggressively.”

 

[member38644]

The findings of this study are extremely significant in understanding the importance of the Y-chromosome in avoiding bladder cancer. The Y-chromosome is responsible for determining male sex characteristics and is also involved in regulating the immune system. As males age and lose their Y-chromosomes, it weakens their immune response, making them more susceptible to cancer.

This study sheds light on the connection between the loss of Y-chromosome and the immune system's response to cancer, specifically bladder cancer. By eluding the immune system, cancer cells are able to grow more aggressively, making it more difficult to treat and potentially more deadly.

These findings emphasize the importance of early detection and prevention of bladder cancer, especially in older males who are more likely to have lost their Y-chromosomes. It also highlights the need for further research on the role of the Y-chromosome in other types of cancer and how it may impact treatment and outcomes.

Overall, this study highlights the significance of the Y-chromosome in not only determining sex characteristics but also in protecting against certain types of cancer. It is a reminder to all males to take care of their health and to be aware of any changes in their bodies as they age.