- #1
baqi
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Deuterium is heavier then Hydrogen so a metal bonded to H vs. C can be determined by isotopic exchange and then using Infrared Spectroscopy/mass spec. But how do you replace hydrogen with deuterium?
a.Dehydrogenation and then add deuterated solvents (heavy water or CDCl3 ..deuterated chloroform)?
b.Just dissolve cpd in deuterated solvent?
I have doubts about the above mentioned applications…so how what is the meachanism?
Thanks for your help
Wait …what is the difference between isotope exchange vs. isotope labeling?
Thanks
a.Dehydrogenation and then add deuterated solvents (heavy water or CDCl3 ..deuterated chloroform)?
b.Just dissolve cpd in deuterated solvent?
I have doubts about the above mentioned applications…so how what is the meachanism?
Thanks for your help
Wait …what is the difference between isotope exchange vs. isotope labeling?
Thanks