Negative pressure and vacuum are distinct concepts; a vacuum is defined as zero pressure, with no possibility of a pressure lower than that. While negative pressure can refer to relative pressure below atmospheric levels, it does not equate to negative absolute pressure, which cannot exist outside specific contexts like quantum field theory. In engineering and chemistry, negative pressure often describes gauge pressure, while in physics, it can relate to phenomena like the ascent of sap in tall trees, where attractive forces exceed repulsive forces. The discussion emphasizes the importance of context when discussing pressure terminology, clarifying that while negative gauge pressure exists, negative absolute pressure is not feasible.