Picking up calculus again after 2 years?

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A biochemistry major has expressed concern about transitioning to multivariable calculus and differential equations after a long gap since completing calculus courses. Despite achieving high grades in calculus 1 and 2, the individual worries about retaining the necessary skills for success in these advanced courses, especially after enjoying physical chemistry that involved some multivariable concepts. Suggestions from the discussion emphasize the importance of self-review, recommending revisiting calculus notes, exams, or textbooks to refresh knowledge. Participants generally agree that if the individual previously understood the material well enough to earn an A, they should be capable of succeeding in the upcoming courses with some review.
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I'm a biochemistry major (chemistry focused, not biology focused program) and I have just completed the fall semester of my junior year. I completed my first semester of physical chemistry (chemical thermodynamics) and I really enjoyed the mathematics. My major only requires calculus 1 and 2, even though physical chemistry required some basic multivariable which I learned on my own. I would like to take multivariable calculus and differential equations, as I am liking the look of more quantitative graduate programs in biochemistry, and I will be working as an undergraduate research assistant in a biophysical chemistry laboratory this spring semester. The problem is that I have not taken calculus since my freshman year, and even though I received an A in calculus 1 and 2, I don't want to crash and burn if I take multivariable calculus and differential equations because I've been away from the material for so long. Has anybody else been in this boat? Does the material come back to you easily? Any comments or suggestions?
 
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You might want to do some self-review. However, if you knew the material well enough to receive an A two years ago, you shouldn’t need any more than this.
 
You should be fine. If you're worried about not remembering how to do something, review your calculus notes/exams if you still have them, or just look online for a review of some sort.

If you still have your calculus book, perhaps doing some review problems wouldn't hurt either.
 
Hey, I am Andreas from Germany. I am currently 35 years old and I want to relearn math and physics. This is not one of these regular questions when it comes to this matter. So... I am very realistic about it. I know that there are severe contraints when it comes to selfstudy compared to a regular school and/or university (structure, peers, teachers, learning groups, tests, access to papers and so on) . I will never get a job in this field and I will never be taken serious by "real"...
Yesterday, 9/5/2025, when I was surfing, I found an article The Schwarzschild solution contains three problems, which can be easily solved - Journal of King Saud University - Science ABUNDANCE ESTIMATION IN AN ARID ENVIRONMENT https://jksus.org/the-schwarzschild-solution-contains-three-problems-which-can-be-easily-solved/ that has the derivation of a line element as a corrected version of the Schwarzschild solution to Einstein’s field equation. This article's date received is 2022-11-15...
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