To prove De Morgan's Law, ~(p ∧ q) = ~p ∨ ~q, without truth tables, natural deduction can be employed. Basic rules of propositional logic, such as the rules of inference, are essential for constructing the proof. The discussion highlights confusion regarding specific rules referenced in natural deduction. Participants suggest consulting resources like Wikibooks for guidance on logical statements. The focus remains on finding a method to prove the equivalence of the expressions as required by the lecturer.