Cosecant, defined as csc(x) = 1/sin(x), is relevant in real-world applications wherever sine functions are used, as it can simplify expressions involving sin(x). The discussion highlights that csc(x) can make mathematical expressions more concise, similar to how numbers like 8 are preferred over lengthy additions. While specific real-world examples are challenging to find, some applications in physics, such as formulas related to friction, may utilize cosecant. A proposed scenario involves two people measuring distances and angles, where the distance can be expressed using csc(w). Overall, understanding csc(x) enhances mathematical efficiency, despite the need to learn additional rules.