Resonance of DNA O-H and N-H bonds?

[Schoenbrau]

Hi, I'm trying to figure out if it is possible to induce (hydrogen) bond breakage between DNA base pairs by resonance. Does anyone know if this is possible or even aware of bond breakage in other molecules by similar methods? Thanks!

 

[alxm]

What do you mean by 'resonance'?

Through the back-and-forth vibrational motion of atoms? Yes, you can break all chemical bonds that way. It's because the vibrational motion of atoms in molecules is a substantial part of what we call 'heat'.