To achieve equal scaling of axes in 2D graphs using Mathematica, adjusting the AspectRatio to 1 is essential for creating perfect squares in the grid. Users should explore the Options[Plot] function to find the AspectRatio setting. Additionally, understanding the difference between PlotRange and PlotRegion can further enhance graph presentation, although the primary focus remains on setting the AspectRatio correctly. There may be more elegant solutions available, but these adjustments are fundamental for achieving the desired visual outcome.