What you are describing is called a 'local hidden variable theory'. That means a theory in which the cat is alive or dead, but the information is hidden from us (by the box, in this case). The word 'local' comes into it because you haven't invoked any global information such as many-worlds theory.
Incidentally, the 'hidden' bit also explains why building a transparent box doesn't help. Nobody disputes that the cat is definitely alive or definitely dead when we are looking. It's what happens when we aren't looking that is under debate and, with a transparent box, we are always looking.
Back to the question - in the 1980s, a chap called John Bell developed the Bell Inequality. Basically, this shows that for a particular two measurements that you can make, one will on average be less than the other if any local hidden variable theory were true. Put simply, you can design a simple gambling game using quantum particles instead of dice. Bell's inequality says that in a universe like you describe, there's a System for playing this game; in a quantum universe the house always wins. Experiments have shown that the house always wins (this is the real world, after all), so local hidden variable theories do not accurately describe the way the world works.
If the idea of an alive-and-dead cat bothers you, there are three options.
1) Deal with it.
2) Many-worlds theory, where the universe splits in two when the box closes. The cat is dead in one and alive in the other; the two universes stay 'in touch' until the box opens when they permanently and irrevocably part ways and you can find out which one you're in. This is a global hidden variable theory - the variable is which universe you are in, and a better definition of 'not local' is hard to come by.
3) Pilot Wave theory, aka de Broglie-Bohm theory. This is another global hidden variable theory, where the hidden variable is a universe-wide, impossible to detect, but nevertheless real 'pilot wave' which guides particles around while leaving the cat apparently dead-and-alive to anyone not looking.
That last reads more skeptical than I intended. There are serious physicists who hold each of these positions. I'm strictly an amateur these days, so withhold judgment. That also means that there's a fourth option, which is 'something I am not aware of'.
Hope that helps.
PS: It's the finding out that the cat is alive or dead that is important, not how you do it. Hearing breathing, monitoring oxygen consumption, and opening the box for a look are all the same in this context.
PPS: Lunchtime reading tells me that Bell's work was done in the 1960s, not the 1980s, and that there are still loopholes in the tests of Bell's Inequality that might permit local hidden variable theories to exist under certain circumstances. How improbable these circumstances are I am unable to judge, but consensus seems to be that the preponderance of evidence is for quantum theory rather than local hidden variables.