The breakdown of molecules using electricity is influenced primarily by the applied voltage and current, with voltage needing to be sufficient to separate the molecules and current determining the breakdown rate. The specific molecule in question also plays a crucial role, as different molecules require varying electric fields for effective breakdown. For some molecules, only a few volts per meter are necessary, while others may need megavolts. The discussion highlights the importance of understanding the chemistry involved in electrolysis and molecular interactions. Overall, the effectiveness of the process depends on both the electrical parameters and the nature of the molecules being broken down.