Structural Questions about Memory B cells

  • Thread starter mktsgm
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  • #1
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Summary:
Is there a structural difference between mature B cells and memory B cells?
I have the following doubts regarding B cells.

Normally upon the stimulation by a T-cell, the activated B-cell differentiates into plasma and memory cells.

1) What are the structural differences among the naive B-cells, activated B-cells, Plasma B-cells, and memory B-cells? I am interested in the comparison of structures of Plasma B-cells and memory B-cells.
2) Is it possible to detect and measure all four?
a) Again I am particularly interested in the Plasma B-cells and memory B-cells for a particular antigen. How do we differentiate between them and can we detect and measure them?

Thanks in advance,
 
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Answers and Replies

  • #3
jim mcnamara
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This would require about 40 pages on the forum.

https://www.academia.edu/40521511/Janeways_Immunobiology_9th_Edition
Janeway Immunobiology 9th ed is in the public domain. Please download the and start reading with the caveat that more details about some more aspects of antibody creation are now known.

If there is acopy of the current 10th edition in a local school library, try that.

Actually the best thing you could do (if you have enough background) is to take a look at courses offered free over the internet. Start with into Virology, then go from there.

What you need is not feasible for PF. And a marginal overview will confuse you unduly.

That's all for now.
 

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