Study of tautomerism using radioactive isotopes

In summary, the conversation discusses the concept of tautomerism and its relation to isomerism. Tautomerism is a form of isomerism where two or more forms of isomers are interchangable and in dynamic equilibrium. Isomerism refers to the formation of molecules with the same chemical formula but different structural formulae. There are several types of isomerism, including positional, structural, functional, stereoisomerism, geometric, and optical. Tautomers are isomers with a low activation energy separating them, often involving the movement of a proton between nearby atoms.
  • #1
Nomy-the wanderer
172
1
I've searched for a simple definition, but i couldn't find an illustrated clear one.

It's about the study of tautomerism using radioactive isotopes, or tracers.
 
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  • #2
Its a form of Isomerism where the two (or more) forms of isomers are interchangable or in dynamic equillibrium, changing from one form to another.

They sit in equillibrium, the equillibrium point can obv be shifted by changing conditions to favour the formation of one of the isomers.
 
  • #3
And ismoerism is formation of another molecule that has the same chemical form and bonding with different arrangement, and hence different chemical and physical properties sometimes...??
 
  • #4
That is correct, there are several types of isomerism.

Positional, structural, functional, steroisomerism, geometric, optical..
 
  • #5
Nomy-the wanderer said:
And ismoerism is formation of another molecule that has the same chemical form and bonding with different arrangement, and hence different chemical and physical properties sometimes...?? [emphasis added]
Isomers are molecules with the same chemical formula but different structural formulae. This necessarily makes the bond geometry different between two isomers.

Tautomers are isomers with a "small" activation energy separating them. They typically involve the jump of a proton between nearby atoms.
 
  • #6
Got it, thanks people.
 

1. What is tautomerism?

Tautomerism is a chemical phenomenon in which a molecule exists in two or more forms that are in equilibrium with each other, and can rapidly interconvert. These forms are called tautomers and they differ in the placement of a hydrogen atom and the double bond in the molecule.

2. How are radioactive isotopes used in the study of tautomerism?

Radioactive isotopes, such as carbon-14, can be incorporated into the tautomeric molecules. The radioactive decay of these isotopes can then be measured, providing valuable information about the rate of tautomeric interconversion and the stability of each tautomeric form.

3. What are the benefits of using radioactive isotopes in this study?

Using radioactive isotopes allows for the tracking and quantification of tautomeric interconversion, which is not possible with other methods. It also provides a more accurate and precise measurement of the rates and equilibrium constants of tautomerism.

4. Are there any risks associated with using radioactive isotopes in this study?

The use of radioactive isotopes does come with some risks, as they are known to be potentially harmful to living organisms. Therefore, proper safety protocols and precautions must be followed in handling and disposing of these isotopes.

5. How does the study of tautomerism using radioactive isotopes contribute to scientific research?

Studying tautomerism using radioactive isotopes can provide valuable insights into the behavior and properties of molecules, which can have implications in various fields such as chemistry, biology, and pharmaceutical research. It can also help in the development of new drugs and understanding molecular mechanisms in biological systems.

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