yes, some bases make calculations easier, a matrix might have a "nicer" form, such as upper triangular, or diagonal, or one might want to make a basis orthonormal, to simplify calcuating inner products.
another reason might be that you have, for example, some data that is given in terms of certain linearly independent functions, but you want to express these in terms of "standard functions". perhaps "cost" is determined by one polynomial, and "productivity" by another polynomial, and you want to express the results in terms of 1,x,x^2,x^3, etc.
sometimes, one basis makes the geometry more transparent, and the spatial relationships more obvious. you might transform a "slanted" space, to one that has perpendicular axes, to get a better feel for what things "look like".