- #1
TytoAlba95
- 132
- 19
- Homework Statement
- While attempting to create a model of poliomyelitis in mice, it was found that the mice cannot be infected with the said virus. Since human beings are susceptible to this viral infection, which kind of transgenic mice should be generated to have a transgenic mouse model that can be infected with polio virus. Select the right approach from below:
- Relevant Equations
- a. A mouse expressing human receptor gene which makes cell surface protein for docking and internalization of polio virus.
b. A mouse expressing human receptor gene which makes cell surface protein for docking and internalization of polio virus along with a gene designed to express surface protein of this virus at puberty.
Ans:a
I think the answer should be (b) and not (a) because to study the mice model, there should be a gene designed to express the protein of this virus on the cell surface (but I don't know the what it has got to do with puberty ).