Although the many break-throughs in so many neurological diseases, Parkinson disease still remains a mystery that affects quite a lot of people directly or indirectly. I have been doing an experiment on Parkinson disease now 4 months and the results are still to be seen when I shall assess the membrane potential of mitochondria present in the midbrain. The results will tell me if a decrease in membrane potential in turn leading to cell apoptosis which causes this degenerative process is or not the pathological change behind this disease. I am using the JC-1 method to assess membrane potential. Well, I would like to have your views and comments on Parkinson disease and what should I do to improve such an experiment, and any questions you would like to ask about the experiment or if any questions you like me to answer.