The main sequence is a crucial phase in a star's lifecycle, representing the period when stars fuse hydrogen into helium. It is plotted on the Hertzsprung-Russell diagram, indicating that stars spend the majority of their lives in this phase. Stars transition to the main sequence from the pre-main sequence stage, becoming Zero Age Main Sequence stars upon initiating hydrogen fusion. The duration of the main sequence varies, lasting hundreds of millions of years for massive stars and up to tens of billions for smaller ones, like our Sun, which has an expected main sequence lifetime of about ten billion years. Understanding the main sequence is essential for tracking stellar evolution and the history of stars.