Physiology or Medicine
Napoleone Ferrara, University of California, San Diego, CA, for the discovery of vascular endothelial growth factor (VEGF), a key regulator of angiogenesis, the process in which new blood vessels are formed, both in healthy tissue and in cancerous cells. Ferrera's work has led to the development of drugs that inhibit blood-vessel growth in cancer and in blinding eye disorders such as age-related macular degeneration.
Minoru Kanehisa, Kyoto University, Kyoto, Japan, for contributions to bioinformatics, specifically for his development of the Kyoto Encyclopedia of Genes and Genomes (KEGG). This database of protein pathways involved in gene expression allows genomicists and other researchers to collect, compare, and interpret data on cellular processes – for example, those that underlie disease.
Solomon H. Snyder, Johns Hopkins University, Baltimore, MD, for his identification of receptors for many neurotransmitters and psychotropic agents, including brain receptors associated with opiates. His insights have been applied in the development of many common prescription drugs, such as compounds for pain control.
Physics
David Awschalom, University of Chicago, IL, and Arthur C. Gossard, University of California, Santa Barbara, CA, for observation of the spin Hall effect in semiconductors. This insight into how electrons behave under the influence of magnetic fields promises application in many areas, including quantum computing.
Sandra M. Faber, University of California, Santa Cruz, CA, for pioneering methods to determine the age, size and distance of galaxies and for other contributions to cosmology, including work on the "cold dark matter" believed to constitute the universe's "missing" matter.
Yury Gogotsi, Drexel University, Philadelphia, PA, Rodney S. Ruoff, IBS CMCM Center and Ulsan National Institute of Science and Technology, South Korea, and Patrice Simon, Université Paul Sabatier Toulouse III - CNRS, Toulouse, France, for discoveries advancing the understanding and development of carbon-based materials including for capacitive energy storage and understanding the mechanisms of operation of supercapacitors.
Chemistry
Eric N. Jacobsen, Harvard University, Cambridge, MA, for contributions to catalytic reactions for organic synthesis, especially for the development of Jacobsen epoxidation.
George M. Sheldrick, Georg-August-Universitat Gottingen, for his enormous influence in structural crystallography through the introduction and maintenance of the SHELX system of computer programs.
JoAnne Stubbe, MIT, Cambridge, MA, for her discovery that ribonucleotide reductases transform ribonucleotides into deoxyribonucleotides by a free-radical mechanism. These deoxyribonucleotides, in turn, are fundamental to the synthesis and repair of DNA.