Why does venous block cause infarction?

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SUMMARY

Venous block can lead to tissue infarction due to congestion and increased back pressure, which impairs arterial blood perfusion despite the continued supply of oxygen. This results in necrosis of the affected tissue. The discussion also highlights that the pathogenesis of cerebral venous infarction differs from that of cerebral arterial ischemic infarction, with the former potentially leading to hemorrhagic infarcts due to prolonged blood retention in the area, reducing oxygen transfer to tissues.

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sameeralord
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Hi guys,

I know this is a simple question. But when an artery is blocked it is easier to understand because, less oxygen goes to tissue so, necrosis of tissue. But when a vein is blocked, only the draining is affected, the arteries are still able to supply oxygen, but why does necrosis still occur. I'm assuming it is because when a vein is blocked, it leads to congestion, increased back pressure, which makes it difficult for arterial blood to come and perfuse tissue. Just asked to clarify (I know this is probably a pretty obvious stupid question, but I like to get it clarified). Thanks :smile:

While we are at it, if you know something about this, please tell me

Does the pathogenesis of cerebral venous infarction differ considerably from the pathogenesis of cerebral arterial ischemic infarction. Why does a haemorrhagic infarct occur in cerbral venous infarction.
 
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You can simply see this as "what flows in must flow out", because if that is not the case some volume of blood will stay in the same area for a prolonged time and the transfer of oxygen to the tissue from this volume of blood will go down as their oxygen levels get closer together.
 

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