If one does a search on "vacuum breakdown", one will obtain A LOT of sources and published papers.
Those of us who work with high-gradient structures can only WISH that (i) there are no breakdown problems and (ii) that we don't detect such a thing when it happens (which means that it doesn't matter!). Both of these are wishful thinking, meaning that such breakdowns do occur in vacuum, and that they can be detected, either from the disruption in the power/fields in the vacuum structure, and from visual evidence of light emission.
The mechanism of vacuum breakdown can be involved and complex. The fact that you have a high gradient means that this is not just an empty space. There has to be at least one surface or source that is at very high potential difference when compared to something else. Otherwise, there will be no field.
Most theories on such a breakdown starts with the emission of field electrons due to the high gradient. These are electrons that tunneled though the material, especially in regions where there are sharp, pointy topography (these are called high field-enhancement regions). At some point, if the field is sufficiently high, these field electron currents actually can heat up the emission sites. Heat implies outgassing of material. So this vacuum that you had before is not as good anymore, because the outgassing introduces species of atoms and molecules into the vacuum, especially around the heating sites. If the field-emitted electrons are energetic enough (after all, it gains energy after it leaves the material due to the external field), it can then ionize the outgassed atoms. And then a series of events can take place, including that the ionized atom (which has the opposite charge than the electrons), will be pushed back into the surface and cause even more stuff to be ejected.
One can already see that in this complex sequence of events, a "casade" of charging-discharging of gas specie can happen, and the excited gas can emit light. This can often lead to the so-called vacuum breakdown. In an accelerator high gradient structure, it absorbs power, ruin the field geometry, and in some cases, leads to catastrophic failure of the structure itself.
So yes, breakdown can happen in vacuum, and yes, they can be seen with the naked eye.
https://www.physicsforums.com/threa...-in-a-straight-direction.891681/#post-5621395
https://www.physicsforums.com/threads/ionization-neutralization-electrical-breakdown-etc.744778/
Zz.