Medical Cerebral small vessel disease does it lead to dementia?

AI Thread Summary
Cerebral small vessel disease (CSVD) is associated with cognitive impairment and can lead to vascular dementia. Individuals with CSVD may experience executive and attentional dysfunction, while episodic memory often remains relatively intact, distinguishing it from Alzheimer's disease. Concerns about developing dementia following a transient ischemic attack (TIA) and CSVD diagnosis are common, especially in younger patients. Monitoring and managing risk factors, such as lipid levels, is crucial for overall brain health. Further research and resources can provide more insights into the relationship between CSVD and dementia progression.
Diamani
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Cerebral small vessel disease...does it lead to dementia?

My mum (51) has recently had a TIA and has been diagnosed with CSVD. She has some dysphasia and memory trouble. She has had bloods...all normal, lipids at 5.5 (put on meds to bring it down to 3.5), carotid dopplers - normal, all vitals are within normal limits, transthorasic echo and tranesophageal echo show normal heart function. She is however very worried about developing small vessel dementia. Does anyone know if SVD leads to dementia?
 
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With the help of our beloved Google I found some information about that:

"Cerebral small vessel disease is a common cause of cognitive impairment and vascular dementia. The cognitive deficit differs from that in Alzheimer's disease, with greater executive/attentional dysfunction and relatively intact episodic memory."

This is from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1739761"
 
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Thank you for your help :)
 
I've been reading a bunch of articles in this month's Scientific American on Alzheimer's and ran across this article in a web feed that I subscribe to. The SA articles that I've read so far have touched on issues with the blood-brain barrier but this appears to be a novel approach to the problem - fix the exit ramp and the brain clears out the plaques. https://www.sciencealert.com/new-alzheimers-treatment-clears-plaques-from-brains-of-mice-within-hours The original paper: Rapid amyloid-β...

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