How does the Circadian clock work in insects like flies?

AI Thread Summary
The discussion centers on the biological and chemical properties of a fly's circadian clock, emphasizing its complex feedback loop mechanism. Key components include transcription factors like Clock and Cycle, which bind to DNA and promote the expression of proteins such as Period and Timeless. These proteins then inhibit the transcription factors, creating a cyclical pattern. Light significantly influences the degradation of the Timeless protein, which is crucial for the clock's function. Additionally, there is mention of deuterium's effect on slowing down the circadian rhythm in flies, indicating potential avenues for modifying their biological clock. The conversation also notes a tendency for repetitive questions, leading to a request for more focused inquiries.
nukeman
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Hey all!

I am having a hard time finding a few specific answers, so thought I would give you biology nutz a question :)

A insect, more specifically, a fly...Can anyone explain the biological/chemical properties of a flies circadian clock? What governs a flies biological clock in terms of its biology ?

Possibly try and answer this based on the knowledge I don't know much about Biology :) and also, in terms of if someone wanted to "adjust or modify" a flies circadian clock.

Thanks
 
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Which clock?
 
Pythagorean said:
Which clock?

Dammn :)

I will have to ask the people who said it. They simply said that:

"Deuterium has been shown to slow down the circadian clock (rythm) of flies"

I want to understand the biological mechanics that govern a fly.
 
It's complex, but simply stated it's a feedback loop. There are transcription factors (Clock, cycle) that bind DNA and stimulate the expression of proteins (Period, Timeless), these inhibit the transcription factors (feedback loop).

The accumulation of Period of Timeless marks one period of the clock, the degradation of the proteins the other. Light plays a major role in the degradation of the protein Timeless. More info here: http://www.sdbonline.org/fly/neural/timeless.htm
 
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