Is it possible to artificially simulate telamores?

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The discussion centers on the potential for creating artificial enzymes that mimic telomerase, particularly through the use of nanocircle DNA, which could significantly benefit the anti-aging community. A recent breakthrough involving a mouse that expressed additional telomerase after a viral infection demonstrated a lifespan extension of 24%, highlighting the relevance of telomerase in aging research. The conversation explores the idea of developing a system for continuous telomerase delivery while considering the challenge of targeting specific cells to avoid cancerous transformations, as nearly any cell can become cancerous under certain conditions. The inquiry reflects a curiosity about the intersection of genetics and aging, despite the participant's limited background in biology.
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Is it possible to create artificial enzymes that can simulate telamores? I read somewhere that nanocircle DNA made this potentially possible. I would think that this would be an extremely helpful addition to the anti-aging community. This makes me wonder if we could somehow create a system in which constant telamorace is being pumped in and replaced; could we also pair this with some sort of modification that would only target specific cells (for instance, avoid potentially cancerous cells)? Please, bear with me. I'm only a high school student; I haven't even took biology yet.
 
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ShiningLegend said:
Is it possible to create artificial enzymes that can simulate telamores? I read somewhere that nanocircle DNA made this potentially possible. I would think that this would be an extremely helpful addition to the anti-aging community. This makes me wonder if we could somehow create a system in which constant telamorace is being pumped in and replaced; could we also pair this with some sort of modification that would only target specific cells (for instance, avoid potentially cancerous cells)? Please, bear with me. I'm only a high school student; I haven't even took biology yet.

Potential Cancer cells? Almost every other cell can turn cancerous under the right conditions (or lack thereof).
 
mishrashubham said:
Potential Cancer cells? Almost every other cell can turn cancerous under the right conditions (or lack thereof).

As I said, please bare with my inexperience.
 
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom

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