Breathing Liquids: Experiments, Tests & Challenges

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Breathing liquids, particularly perfluorocarbons, have shown promising results in experiments, with rats surviving for up to 20 hours while breathing these substances. Current research is exploring the potential for human applications, particularly in medical scenarios such as aiding premature infants with underdeveloped lungs. While there have been advancements, significant challenges remain, including safety, efficacy, and the physiological impacts on human lungs. The use of highly oxygenated fluids in neonatal care has been noted, but comprehensive human trials on breathing liquids are still limited, indicating that further investigation is needed before widespread application can occur.
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In the past experiments have been done with breathing liquids. Rats did survive up to 20 hours while breathing perfluorocarbons. What is the current status on this? Has it already been tested on people? Or are there major problems?
 
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I seem to have heard that some prematurely born babies with underdeveloped lung capacity is given a highly oxygenated fluid to breathe in.
I'm not too sure about this, though..
 
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