It is possible to compile a MATLAB program into a standalone application that does not require MATLAB to run on either Mac or PC. Users can access MATLAB's documentation by typing 'doc mcc' within MATLAB for guidance on the compilation process. The MATLAB Compiler is necessary for this task, but it is an additional toolbox not included in the standard MATLAB distribution. While the MATLAB Compiler incurs extra costs, it is relatively inexpensive compared to the full MATLAB software. Compiling MATLAB programs allows for broader accessibility and usability across different operating systems.