In general, unless you already have a good background in the subject of a textbook, you should not try to pick and choose; you should just read the textbook and work the problems.
I would say this is backwards; the fact that the properties of electricity and magnetism (and, as we now know, the properties of all fundamental interactions) are Lorentz invariant, rather than Galilei invariant, is what makes relativity the correct theory, rather than non-relativistic mechanics.
It depends on how you interpret that equation. The best current interpretation is that it is simply an expression of a unit conversion: the conventional units of energy are the conventional units of mass, times ##c^2##. In itself this equation says nothing about whether rest mass and other forms of energy can be inter-converted.
It is true that no one has ever developed a non-relativistic theory in which rest mass and other forms of energy can be inter-converted, for example by a particle and antiparticle annihilating each other and producing radiation. However, that could just be due to historical accident--that by the time experiments showed that such reactions were possible, relativity had already been developed and shown to give more accurate predictions in many other experiments, so there was no incentive to try to develop a non-relativistic theory of such reactions. In itself this does not prove that a non-relativistic theory of such things is impossible, or that they would be impossible in a hypothetical alternate universe where relativity was not true.
More generally, claims of the sort Kaku is making are not claims about physics anyway. They are just sensationalistic claims made to sell books, articles, and TV shows. Neither Kaku nor anyone else can do experiments in some alternate universe in which relativity is not true, so nobody knows for sure what would or would not be possible in such a universe.