Bacteriophages can cross the blood-brain barrier (BBB), but not all types are capable of doing so. Filamentous bacteriophages show promise as carriers for delivering medication past the BBB, while the ability of other phages to penetrate depends on various factors, including the specific type of phage and the state of the BBB during infections. The discussion highlights that while bacteriophages are abundant, their effectiveness in therapy is limited by their inability to infect human cells and the immune system's defenses. Research continues into the therapeutic potential of phages, but challenges remain in their application for treating infections within the central nervous system. Overall, the diversity of bacteriophages complicates the question of their ability to cross the BBB universally.