Early 1900's Concentration Measurements

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The discussion centers on the interpretation of concentration measurements from early 1900s papers, specifically terms like M/4, M/8, M/16, M/32, and M/256. These notations represent molar concentrations expressed as fractions, where M/4 equates to 0.25 M (or 250 mM) in contemporary terms. The use of these fractions, which are powers of 2, stems from a standard practice of preparing a 1 M solution and subsequently diluting it in a systematic manner to create lower concentrations. This method of dilution involved taking a known volume of the concentrated solution and diluting it to a specific volume, allowing for precise control over concentration levels.
Rogers40
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I have read a few papers that were written in the early 1900's where their concentration measurements are M/4, M/8, M/16, M/32, M/256. I am not sure what this means and I was wondering if anyone could relate these concentration measurements to normal concentration measurements we use now, such as Molar. An example of a paper that used this method of measuring concentration is linked below.
http://ebm.rsmjournals.com/content/23/1/66.extract

I have searched google and had no luck finding what the M/number concentration measurement means. If anyone could find out what this means it would really help.
 
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Rogers40 said:
I have read a few papers that were written in the early 1900's where their concentration measurements are M/4, M/8, M/16, M/32, M/256. I am not sure what this means and I was wondering if anyone could relate these concentration measurements to normal concentration measurements we use now, such as Molar. An example of a paper that used this method of measuring concentration is linked below.
http://ebm.rsmjournals.com/content/23/1/66.extract

I have searched google and had no luck finding what the M/number concentration measurement means. If anyone could find out what this means it would really help.

The M/4 concentration expression is simply an ordinary molar concentration expressed as a fraction rather than a decimal. So a M/4 concentration really means simply a 0.25 M or a 250 mM solution in modern terms.

The reason for the fractions being powers of 2 is also a very simple one: It was standard practice to make up a 1 M solution, and then prepare a series of dilutions by pipetting a 50 mL aliquot, and making up to 100 mL in a volumetric flask and then repeating that procedure several times to obtain a M/2, M/4, M/8, M/16 etc. series.
 
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