Factors That May Influence Susceptibility to SARS-Cov-2: A Statistical Analysis

AI Thread Summary
The discussion centers on the relationship between immunity-related illnesses and the severity of SARS-CoV-2 infections. Participants express a need for statistics on patients with pre-existing immunity issues and their outcomes during the pandemic. It is noted that immune suppression generally increases risk, particularly among the elderly, whose compromised immune systems may contribute to higher mortality rates. The conversation touches on the complexity of immune responses, including the potential for both underactive and overactive immune reactions to affect COVID-19 severity. There is speculation about unidentified immune conditions that could exacerbate the virus's lethality, emphasizing the need for more research and data collection. References to existing studies highlight the presence of certain immune deficiencies, like HIV, in some COVID-19 patients, but there is a call for broader investigation into other possible immunity-related factors influencing outcomes. Overall, the dialogue underscores the intricate interplay between immune health and COVID-19 susceptibility.
hagopbul
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TL;DR Summary
There is few information regarding statistics I couldn't find on the net
Hello all:

Hope all are fine and well , there is this question in relation to corona virus problem :

Do anyone checked if the patients have any immunity related illnesses with the patients of SARS-Cov-2

Where I can find those statistics

Best regards
Stay safe
 
Biology news on Phys.org
no information on the site if the patients had some kind of immunity illness or they took an immunity illness tests during the SARS-COV-2 period

do you know an expert working in an immunity lab i can correspond with ?
 
Wasn't the auto-immune disease question the reason for folks looking at Hydroxychloroquine ? I believe that is what you should research...people are already looking.
 
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I don't think such figures would be considered useful. It is generally accepted that immune suppression puts someone at increased risk, and the people involved are aware of this and could be expected to be taking extra precautions. It is assumed one of the reasons the elderly are more at risk is because their immune system is less effective. However this is complicated by the idea that a significant cause of death is due to an immune over response, which is currently treated with drugs designed to suppress this response.
I suspect that because of the actions to protect the immune compromised individuals and the delays in treatments that would cause immune suppression, if we treat the elderly as belonging to a different risk category, the numbers would be low and unrepresentative.
We might get some more information when they start reporting on vaccine trials but until then I suspect that any information will be based on theoretical risks.
 
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i was wondering if the patients had an immunity problem before SARA-Cov-2
 
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atyy said:
This paper mentions problems that patients had before COVID-19. A small number of patients had HIV (not sure if that is the sort of immunity problem you were asking about):
https://jamanetwork.com/journals/jama/fullarticle/2761044

no i wonder if there is other immunity related thing that results in the fatality of SARS-COV-2
the fatality of this illness is 3.4 - 14%
could there is some sort of immune illness that make the SARS-COV-2 dangerous, some illness we don't know about ? if you don't test the patient blood will not be seen ?

hope all of you are safe and fine
 
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what if 1st was the immune system was weaken for reasons we don't know then if the SARS-cov-2 hit the person it became lethal , like the SARS-Cov-2 lethality is an outcome of some immune system illness
 
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Well there are lots of individual differences in people which might alter a persons susceptibility to any infection and then a huge set of environmental issues that might alter risk, so unless there is a clear single issue identified, like diabetes it will be impossible to get a clear answer.
So, yes immune competence is extremely important but there is a big list of things that might effect that.
 
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