What exactly is a genetic vaccine and how does it differ from a DNA vaccine?

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A genetic vaccine refers to a vaccine derived from the genetic material of a pathogen, often involving genetic engineering or recombination techniques. It is commonly associated with DNA vaccines, which utilize DNA to provoke an immune response. Currently, most genetic vaccines are still in clinical or animal trials, with no commercial options available yet. Additionally, there is a growing interest in RNA vaccines, which may also fall under the umbrella of genetic vaccines. The terminology is evolving as research progresses in this field.
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Is a genetic vaccine simply another word for a genetic engineering/genetic recombination? It is part of a question on my microbio. homework but we have never talked about the exact phrase "genetic vaccine" so I am a little confused as to what exactly it is referring to. Thanks for the help!

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I take it to mean a vaccine derived from the genetic material of a pathogen. Ask your prof for a better answer - the one he expects you to know.

See an old overview clip meant for a general audience:
http://www.sciam.com/article.cfm?articleID=000BAB9A-99E7-1CD6-B4A8809EC588EEDF

There has been a lot of research on them since 1999. Maybe Moonbear knows if there are extant vaccines. I do not.
 
Genetic vaccine are also called DNA vaccine.

As far as the vaccine goes, it's all clinical or in animal trials. There is no commercial vaccine available.
 
Ian -
Are there no RNA vaccines? Or more correctly no possiblilty of them...
 
I think there's some RNA vaccines in clinical trials, it's probably why the term Genetic vaccine are now name so. I learned all about DNA vaccine as an undergrad but RNA never came up.
 
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) he structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom
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