To find the heat transfer rate in a tube with air entering at a specific temperature and pressure, the equation Q = mCp(Delta T) can be used, where Q is the heat rate, m is the mass flow rate, Cp is the specific heat, and Delta T is the temperature difference. If the mass flow rate is not provided, it can be derived from the air's velocity and cross-sectional area using fluid flow equations. The discussion emphasizes the need to consider pressure drop and heat transfer, suggesting that numerical methods may be necessary for complex scenarios. It is also noted that if the cross-sectional area is known, velocity can be assumed constant, simplifying the calculation. Understanding these principles is crucial for accurate heat transfer analysis in fluid systems.