To find the equation of the line perpendicular to -8y - 8 - 16x = 0 and passing through the point (18, 0), first, rearrange the original equation to the slope-intercept form to identify the gradient. The gradient of the given line is 2, so the gradient of the perpendicular line will be -1/2. Using the point-slope form with the point (18, 0), the equation can be derived. Understanding the relationship between parallel and perpendicular lines is crucial, as parallel lines share the same slope while perpendicular lines have slopes that multiply to -1. The solution involves substituting the point into the derived equation to find the specific line.