Holding your breath can lead to serious consequences for brain function, with permanent damage potentially occurring after just three minutes of apnea. Most individuals will faint and resume breathing involuntarily before reaching this critical point. The inability to breathe causes carbon dioxide to accumulate in the blood, leading to a dangerous drop in pH and stimulating the brain's respiratory center. Generally, after 5 to 10 minutes without breathing, the risk of severe and irreversible brain damage increases significantly. However, under specific conditions like hypothermia, individuals—particularly children—may survive longer periods without lasting harm, as lower body temperatures can slow metabolism and reduce damage. This phenomenon is sometimes referred to as suspended animation, which has been explored in research contexts, although some studies have faced withdrawal.