To calculate the change in head when reducing the discharge line size from 8" to 6", it's essential to consider the entire system's details, including pipe length and connections. The increased velocity in the smaller pipe will lead to higher pressure requirements, calculated using Bernoulli's principle and affinity laws. Online calculators can assist in determining pressure loss based on pipe material, diameter, and fluid details. The discussion emphasizes that small changes in lift can significantly affect flow rates, especially when operating near the pump's maximum head. Ultimately, the impact of pipe size on head loss is minimal compared to elevation gain in this specific scenario.