Define a custom format and use it whenever you create a new graph of the same type:
First, set up a graph the way you want it: chart type, axis scales, gridlines, title, axis labels, etc.
Then, go to the Chart menu and choose Chart Type.
At the top of the window, select the Custom Types tab.
In the Select From box, choose User-defined.
Click the Add button. It will ask you to give your new custom type a name and an optional description.
Now, when you want to create a new graph of this type, select the data that you want to include, then click the Chart Wizard button. In the Chart Type window, choose the Custom Types tab, then the User-defined button, then your custom type.
If you're making a lot of these one after the other, you can make the type your default type, and then I assume it will automatically be selected when you enter the Chart Wizard. I haven't tried it myself.
Disclaimer: this is for the Macintosh version of Excel, in MS Office X. The procedure may be different in other versions of Excel.