Determining the number of bolts on a flange requires specific details about the application, including pressure ratings and flange dimensions. For a flange diameter of 335 mm and bolt size M12, consulting local codes and flange rating charts is essential to ensure proper design. Flange manufacturers' websites can provide detailed specifications and calculations. The pressure rating is crucial in deciding the appropriate number of bolts needed for safety and functionality. Accurate calculations and adherence to standards are necessary for effective flange design.