If the pressure drop is not too large (say less than about 10%), you could approximate the air as being incompressible, and use the basics for the pressure drop/flow rate relationship: The pressure gradient is equal to the friction factor f times ρv2/2 times 4/D, where v is the cross section average velocity and D is the diameter, and where the friction factor is a known correlated function of the Reynolds number (unless the flow is laminar (Re<2100), in which case the friction factor is exactly 16/Re). If the flow is compressible (i.e., the pressure drop is too large), the calculation is a little more difficult, but no big problem. To find out how to do it for a compressible gas, see the oil and gas handbooks.