The zero state response (ZSR) is defined as the system's response when all initial conditions are zero, meaning it is inherently unaffected by initial conditions. In systems of order two or higher, both the initial value and slope of the response will also be zero. While the response remains consistent regardless of initial conditions, any excitation will keep the system in the zero state. The discussion highlights a misunderstanding about the correlation between initial conditions and ZSR, emphasizing that ZSR calculations exclude initial conditions. Ultimately, ZSR will yield the same result irrespective of initial conditions, reinforcing its definition.