Is there any study about how enzyme work on level atom

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Research on enzyme function at the atomic level has advanced significantly, primarily through techniques like x-ray crystallography, NMR spectroscopy, and electron microscopy, which provide detailed three-dimensional structures of enzymes. These structural insights help identify the specific regions involved in catalysis and regulatory mechanisms. Additionally, computational methods such as molecular dynamics simulations are employed to further explore enzyme catalysis. Biochemistry textbooks typically cover these topics, and the Protein Data Bank serves as a valuable resource, offering access to atomic resolution structures and informative features about various enzymes and their functions.
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Is there any study about how enzyme work on level atom ?
where i can read about subject ?
 
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There has been a lot of work about how enzymes work at the atomic level. Most studies have used x-ray crystallography (and increasingly NMR spectroscopy and electron microscopy) to determine the three-dimensional structures of enzymes at atomic resolution. These pictures of enzymes can help reveal which parts of the enzyme are involved in performing catalysis and reveal regulatory mechanisms. Using these enzyme structures, biologists can then study enzyme catalysis computationally using molecular dynamics or other types of computer simulations.

Most biochemistry textbooks should talk about enzyme catalysis and mention structural studies of enzymes. The Protein Databank (http://www.rcsb.org/pdb) is a repository for atomic resolution structures of proteins, and it's molecule of the month feature talks about many enzymes and how they work.
 

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