To find the latitude and longitude of the most northern point on a great circle route from Vancouver to New York, one must express the coordinates of both cities in three-dimensional Cartesian coordinates. The discussion emphasizes using vector mathematics, specifically the cross product to determine a vector perpendicular to the great circle path, and the dot product to find the angle between this vector and the geocentric z-axis. The angle derived from these calculations indicates the latitude at which the route transitions from traveling northeast to southeast. The coordinates for Vancouver are provided as (N49 12 00, W123 14 00) with Earth's radius set at 6372 km. Understanding these vector operations is essential for solving the problem effectively.