The lense has to be transparent to that frequency of light. For example, glass is quite transparent to visible light, while opaque to thermal IR. Silicon, on the other hand, is transparent to IR and opaque to visible light. Admittedly I do not know the transparencies of different materials to gamma radiation, but as it has such a high energy, as it passes through materials it is most likely going to interact and make a good number of elementary particles.
As for looking at things briefly, you would need very many focused gamma rays, wihch would probably destroy your sample. It would be like trying to figure out the shape of an aluminium goose with a 22.
Electron microscopes are a little more damaging at those wavelengths, yes, but they can be produced fairly easily. If you want to go smaller, you can turn to a scanning/tunnellig microscope for extremely detailed looks, easily finding details smaller then an atom. They have used EM waves to picture a single atom, but from what I remember the picture was a green dot a few pixels across on a black background.
Now, if you want to get fairly technical, in Bose-Einstein Condensates, the many atoms there share one wave function, effectively making one atom in many places. We have pictured these with light, as well as many other techniques. In the process of taking the picture, we destroy the condensate, but it works.