Phys courses for biology research

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Discussion Overview

The discussion revolves around the selection of physics and mathematics courses for a student pursuing a career in biological research, particularly in molecular and structural biology. Participants explore the relevance of various physics and chemistry courses to the student's future research endeavors.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested
  • Homework-related

Main Points Raised

  • One participant outlines a proposed coursework plan including modern physics, thermodynamics, and quantum mechanics, questioning their relevance to bio research.
  • Some participants suggest that a solid foundation in organic chemistry and biochemistry is essential for a career in cell and molecular biology.
  • There is a discussion about the importance of thermodynamics and statistical mechanics, with some arguing that quantum mechanics is not central to biology but beneficial for understanding certain techniques like NMR.
  • Another participant notes that the relationship between physical chemistry and upper-division physics courses is complex, emphasizing the breadth of topics covered in physical chemistry that may be relevant to biology.
  • Concerns are raised about the depth of understanding gained from physical chemistry versus physics courses, with some suggesting that physical chemistry may provide more applicable knowledge for biological contexts.
  • One participant expresses uncertainty about their future research focus but desires a strong foundation in the sciences, leading to a suggestion that any of the proposed courses could be beneficial.

Areas of Agreement / Disagreement

Participants generally agree on the importance of a strong foundation in both chemistry and physics for biological research, but there are competing views on the relative value of physical chemistry versus physics courses. The discussion remains unresolved regarding the best course selection for the student's specific interests and future research direction.

Contextual Notes

Participants mention limitations in course availability and teaching quality, which may influence the decision-making process. There is also an acknowledgment of the varying relevance of different courses depending on the specific area of research within molecular biology.

Who May Find This Useful

This discussion may be useful for students considering a career in biological research, particularly those interested in the intersection of physics, chemistry, and biology, as well as those seeking advice on course selection in STEM fields.

kamikaze1
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Hello, I'd like to pursue a career in bio research (MD/PhD), preferably in molecular, structural bio alike. I plan to minor in phys and math and would like some guidance in coursework. I'll take:

Modern phys (trans to upper division phys course)
Math methods in physics
Theoretical mechanics
Thermodynamics
int ro to Quantum mechanics (1 to 2 semesters)

Math courses
Intro to higher math
Calc of sevreral varariables (taking it now)
Intro to diffeq
Linear algebra
Qualitative ordinary differential equation (more advanced course)
Graph theory
Math bio.

I plan to take intro to quantum mechanics in my senior yr, the 2nd semester course will have time conflict with math bio; i wonder if these phys courses will serve me well for bio research in the future. I know thermodynamics is really important in protein science, but will i be better off taking the chem sequence? I'm not too crazy about chem because the class, from wat I've hrd is poorly taught. The phys chemistry sequence (2 semester) cover thermochemistry and quantum chemistry, but i figure it maynot be as in depth as that in phys. which one should I take?
How will quantum mechanics play a role in molecular biology? How will it help exactly if I were to pursue a career in research (MD/PhD programs)
 
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What is your major? If you are serious about pursuing cell&molecular biology, you should get some serious exposure to organic chemistry/biochemistry as well.

Thermo is definitely an essential background- so is statistical mechanics. QM per se does not play a large role in biology, but understanding QM is not a bad thing and it's needed to understand certain measurement techniques like NMR and its variations.
 
Andy Resnick said:
What is your major? If you are serious about pursuing cell&molecular biology, you should get some serious exposure to organic chemistry/biochemistry as well.
This. A solid, year long sequence in organic chemistry followed by bioorganic wouldn't hurt. It's also not a bad idea to take an inorganic course.

What chemistry courses are bad at your school? Physical chemistry wouldn't be a bad idea as thermodynamics in a chemistry department generally spends more time on topics of interest to a biologist than in a physics department.
 
I'm a biochem major at the same time, so I'll have 2 semesters of organic as well and plenty of bio classes. not too crazy about them since lots of classes are repetitive. The phys chem sequence is 2 semesters, i don't think i have enough spots to put them in my schedules; i jst think the phys. has more theoretical foundation, and it matches well to obtain a minor in phys (jst enough courses)
 
One thing to keep in mind is that the correspondence between a year-long sequence in physical chemistry and upper-division courses in quantum mechanics and thermal physics isn't quite that clear. There's usually more exposure to material involving chemical bonding and spectroscopy, to say nothing of (bio)chemically relevant applications of thermodynamics, reaction kinetics, and usually some surface & solids chemistry. Of course, the trade-off is depth for breadth, although it's typically made up later on (when my one graduate co-advisor taught quantum for chemistry grad students, he used the doorstop, err, the Cohen-Tannoudji two-volume QM text).

I suppose the question is - what is it that you envision yourself doing in structural/molecular biology research? There are plenty of people who basically just crank out structures of (reasonably) interesting and biologically relevant macromolecules with the appropriate biochemical data and (if possible) in vivo studies as a complement. People doing methods development (e.g., devising new NMR pulse programs or scattering techniques) generally will need a deeper appreciation of the underlying formalisms, although it's usually something which is picked up outside of the classroom and within a research group via group meetings, tutorials, and so on.
 
I'd like to have a strong foundation in the sciences. I have no idea wat sort of research I'll do later
 
kamikaze1 said:
I'd like to have a strong foundation in the sciences. I have no idea wat sort of research I'll do later

In that case...honestly, it almost doesn't matter. Any of the paths you outlined would set you up well for further research. I'd pick the courses that are taught by the most dynamic and instructive faculty. One really interesting thing about structural/molecular biology is that people come to the field from all over the natural sciences and engineering.
 
thanx
 

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