Replenish Gut Flora: Options Beyond Fecal Transplant

  • Thread starter Thread starter wywong
  • Start date Start date
  • Tags Tags
    Gut
AI Thread Summary
Antibiotics can disrupt the balance of gut bacteria by eliminating beneficial species, leading to concerns about how to replenish them without resorting to fecal transplants. Common suggestions include adopting a healthy diet and using probiotics, although there is skepticism about their effectiveness in permanently restoring gut flora. Probiotics may only provide transient benefits, altering gene expression in existing gut microbes rather than establishing lasting colonies. Additionally, many probiotic products contain limited strains, which may not be sufficient to replace lost microbiome diversity. While soil-based organisms are mentioned as a potential option, scientific support for their efficacy is lacking. It's advised to consult a doctor before self-treating with probiotics or other supplements.
wywong
Messages
146
Reaction score
6
Antibiotics often killed off good bacteria species in our guts. Are there any ways to replenish them, other than the unpleasant fecal transplant procedure?

A search on this topic mostly return recommendations on healthy diet and probiotics. I reckon these can only help surviving species, and those species that have been eradicated are gone for good. Or could their kin somehow re-colonize our guts?

Some suggest soil-based organisms, but I am unable to find any supporting scientific evidence.
 
Biology news on Phys.org
You can take capsules of bacteria, which in the US can be obtained from your pharmacist without a prescription. But, as always, ask your doctor before self treating since they know your history.
 
Do you mean those sold as probiotics? My understanding is that those bacteria strains are transient in our gut; they don't colonize. For example

The investigators showed that the probiotic product did not change the gut's overall bacterial composition, but instead altered gene expression patterns relevant to carbohydrate metabolism in the host's resident gut microbes.[14] These changes in the human fecal "metatranscriptome" were transient, confined only to the time of the probiotic consumption. Thus, if sustained benefit from a probiotic is desired, continued consumption is likely required.

from http://www.medscape.com/viewarticle/770468_3

Also those probiotics often contain only a few strains, which do not seem enough to make up the loss of the microbiome.
 
Your link doesn't work for me.

The type I took worked for me and the antibiotic I was on was meant to completely wipe out my bacteria, because I had an infection that would not go away, so I had to take the capsules daily, it was a 30 day course, like I said, talk to your doctor. This thread is closed as we cannot go into anything more specific.

Here is an explanation of when fecal transplantation would be considered.

http://www.hopkinsmedicine.org/gast...advanced_endoscopy/fecal_transplantation.html
 
Last edited:
  • Like
Likes Fervent Freyja
Deadly cattle screwworm parasite found in US patient. What to know. https://www.usatoday.com/story/news/health/2025/08/25/new-world-screwworm-human-case/85813010007/ Exclusive: U.S. confirms nation's first travel-associated human screwworm case connected to Central American outbreak https://www.reuters.com/business/environment/us-confirms-nations-first-travel-associated-human-screwworm-case-connected-2025-08-25/...
Chagas disease, long considered only a threat abroad, is established in California and the Southern U.S. According to articles in the Los Angeles Times, "Chagas disease, long considered only a threat abroad, is established in California and the Southern U.S.", and "Kissing bugs bring deadly disease to California". LA Times requires a subscription. Related article -...
I am reading Nicholas Wade's book A Troublesome Inheritance. Please let's not make this thread a critique about the merits or demerits of the book. This thread is my attempt to understanding the evidence that Natural Selection in the human genome was recent and regional. On Page 103 of A Troublesome Inheritance, Wade writes the following: "The regional nature of selection was first made evident in a genomewide scan undertaken by Jonathan Pritchard, a population geneticist at the...

Similar threads

Replies
4
Views
5K
Replies
6
Views
11K
Replies
78
Views
12K
Replies
1
Views
10K
Back
Top