Using Cartesian coordinates to describe points on the surface of a sphere leads to the incorrect conclusion that the space is flat, as all derivatives of the metric vanish. This is because Cartesian coordinates are suitable for flat spaces, while the surface of a sphere is intrinsically curved, requiring spherical coordinates for accurate representation. The discussion emphasizes that any two-dimensional coordinate system on the sphere cannot yield a flat metric, as the surface retains its curvature regardless of the coordinate choice. Furthermore, while Cartesian coordinates can be used locally for flat approximations, they do not capture the intrinsic properties of the sphere's surface. Ultimately, the conversation highlights the distinction between intrinsic and extrinsic curvature in geometry.