Kant (1724-1804) argued that a priori knowledge exists. That is that some things can be known before [without] reference to our senses. Hume (1711-1776) argued that only a posteriori knowledge exists; knowledge is gained exclusively after perception through senses.
Hume promoted a more pure form of empiricism where passion ruled while Kant believed rational thought gave form to our observations.
So Hume would point out that any "gut feeling" is just that. Perhaps with more observation, the confidence limit could approach zero, but it couldn't ever reach zero.
Kant might argue that with proper math, the limit could be made arbitrarily small. But the key would be well reasoned math and a good model.
So there's an open question about the relationship between "the map and the territory". Can a model be made so precise that it becomes the territory? Or in more modern terms, do we live in The Matrix? In a digital universe, the two can be identical. In a chaotic universe (in the mathematical sense), they cannot be.
IMO, science today should assume the least restrictive option, that the map is not the territory. Models represent reality, but are not reality. Perhaps that is not true, but assuming the opposite could lead to errors where we assume a poor map is better than it is.
Still, this borders on matters of faith, and peoples' basic motivations in persuing science. I would not to discourage others from seeking their own truths.