If the static pressure in the supply duct is higher than in the return duct of an Air Handling Unit (AHU), there is no direct effect on system performance, as the two pressures are not interrelated. Typically, the static pressure of the return air is lower than that of the supply air due to downstream control and distribution devices. According to Bernoulli's principle, the static pressure in the discharge plenum must always be higher than in the supply duct. Therefore, while variations in static pressure can occur, they do not impact the overall functionality of the AHU. Understanding these pressure dynamics is essential for effective HVAC system design and operation.